Evidence map›Paper›PMID 40615586›Full record

ArticleDysphagia2026

Effect of Bolus Volume on Upper Esophageal Sphincter Opening: Kinematic Analysis Using 320-Area Detector Computed Tomography.

Keiko Aihara, Marlís González-Fernández, Michele Singer, Eiichi Saitoh, Howell Henrian G Bayona, Yohei Otaka, Yoko Inamoto

Abstract read
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In one paragraph

Article in Dysphagia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Keiko AiharaFaculty of Rehabilitation, School of Health Sciences, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan. keiko-a@fujita-hu.ac.jp.ORCID http://orcid.org/0000-0001-8703-434X
Marlís González-FernándezDepartment of Physical Medicine and Rehabilitation, School of Medicine, Johns Hopkins University, Baltimore, USA.
Michele SingerDepartment of Physical Medicine and Rehabilitation, School of Medicine, Johns Hopkins University, Baltimore, USA.
Eiichi SaitohDepartment of Physical Medicine and Rehabilitation, School of Medicine, Johns Hopkins University, Baltimore, USA.
Howell Henrian G BayonaGraduate School of Health Sciences, Fujita Health University, Toyoake, Japan.
Yohei OtakaDepartment of Rehabilitation Medicine, School of Medicine, Fujita Health University, Toyoake, Japan.
Yoko InamotoFaculty of Rehabilitation, School of Health Sciences, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to determine the impact of bolus volume on UES opening. Twenty-two healthy subjects (10 males and 12 females, 23-45 years) underwent a CT scan while swallowing 3-, 10-, and 20 ml of thin liquid. Upper esophageal sphincter (UES) cross-sectional area and hyoid and laryngeal displacement were measured at every frame across three conditions. The timing of UES opening onset, UES maximum opening, and duration of UES opening were also measured. With increasing bolus volume, the UES maximum opening area increased, at the UES opening onset, at the UES maximum opening was earlier, and the duration of the UES opening prolonged. The maximum displacement of the hyoid and larynx was significantly more anteriorly and higher with a large bolus volume. However, the hyoid displacement at the timing of UES maximum opening did not change across three bolus volumes. This result suggests that the increase in the UES maximum opening area with increasing bolus volume was modulated by the bolus itself rather than by the hyoid movement.

Indexed as

DeglutitionEsophageal Sphincter, UpperAdultBiomechanical PhenomenaFemaleHumansHyoid BoneLarynxMaleMiddle AgedTomography, X-Ray ComputedYoung AdultDeglutitionHyoidLarynxRehabilitationSwallowingUpper esophageal sphincter

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.