Evidence map›Paper›PMID 40615457›Full record

ArticleScientific reports2025

The role of sodium pyruvate in mitigating the cytotoxic effects of vanadium on CHO-K1 cells.

Iwona Zwolak, Ewa Wnuk, Elżbieta Kochanowicz

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Iwona ZwolakDepartment of Biomedicine and Environmental Research, Institute of Biological Sciences, Faculty of Medicine, The John Paul II Catholic University of Lublin, Konstantynów Ave. 1J, 20-708, Lublin, Poland. iwona.zwolak@kul.pl.ORCID http://orcid.org/0000-0003-1780-1763
Ewa WnukDepartment of Biomedicine and Environmental Research, Institute of Biological Sciences, Faculty of Medicine, The John Paul II Catholic University of Lublin, Konstantynów Ave. 1J, 20-708, Lublin, Poland.
Elżbieta KochanowiczDepartment of Molecular Biology, Institute of Biological Sciences, Faculty of Medicine, The John Paul II Catholic University of Lublin, Konstantynów Ave. 1I, 20-708, Lublin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vanadium is a hazardous, pro-oxidant element that contributes to environmental pollution and has been reported as a risk factor for human health through occupational or environmental exposure. Pyruvate, on the other hand, is a natural alpha-keto acid with exceptional antioxidant and cytoprotective properties. Therefore, the aim of this study was to evaluate the mitigating effect of exogenous pyruvate against vanadium-induced toxicity in cultured Chinese hamster ovary (CHO)-K1 cells. To this end, CHO-K1 cells were exposed to 100 μM vanadyl sulfate (VOSO

Indexed as

Pyruvic AcidVanadiumAdenosine TriphosphateAnimalsAntioxidantsApoptosisCell ProliferationCell SurvivalCHO CellsCricetinaeCricetulusGlutathioneMiceOxidative StressVanadium CompoundsAdenosine TriphosphateAntioxidantsGlutathionePyruvic AcidVanadiumVanadium Compoundsvanadyl sulfateAntioxidantApoptosisMetalOxidative stressPyruvateVanadium

Identifiers

PMID40615457
PMCPMC12227759

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.