Evidence map›Paper›PMID 40615152›Full record

SynthesisBMJ mental health2025

Universal, selective and indicated parenting interventions to prevent the development of adverse mental health outcomes in youth: a meta-review of systematic reviews.

Meredith X Han, Edward Chesney, Valerie Ng, Joanna Bright, Yashna K Sagar, Ellie Baker, Michael J Meaney, Evelyn C Law

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Teacher-Led Universal Eating Disorder Prevention Programmes in Schools: A Scoping Review.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  6. Exploring causal mechanisms of psychosis risk.Neuroscience and biobehavioral reviews · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Meredith X HanSocial, Genetic and Developmental Psychiatry Centre, King's College London Institute of Psychiatry, Psychology and Neuroscience, London, UK.ORCID 0000-0002-9467-6700
Edward ChesneyDepartment of Addictions, King's College London Institute of Psychiatry, Psychology and Neuroscience, London, UK.ORCID 0000-0003-2851-5252
Valerie NgInstitute for Human Development and Potential, Agency for Science Technology and Research, Singapore.ORCID 0009-0000-6692-5397
Joanna BrightSocial, Genetic and Developmental Psychiatry Centre, King's College London Institute of Psychiatry, Psychology and Neuroscience, London, UK.ORCID 0000-0002-0695-0491
Yashna K SagarDepartment of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0000-0002-8431-6445
Ellie BakerSouth London and Maudsley NHS Foundation Trust, London, UK.ORCID 0000-0002-9665-3406
Michael J MeaneyDepartment of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Evelyn C LawDepartment of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore paelecn@nus.edu.sg.ORCID 0000-0003-4683-7220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreventive interventions in the form of parenting support can reduce the risk of mental disorders in children. Summarising the effectiveness of parenting interventions across different levels of prevention can inform the prioritisation of the intervention.

objectivesWe conducted a meta-review of systematic reviews and meta-analyses on universal, selective and indicated parenting interventions to prevent adverse mental health outcomes in youth. STUDY SELECTION AND ANALYSIS: PubMed, Ovid, Embase and PsycNet were searched. Systematic reviews consisting of randomised controlled trials of preventative parenting interventions were included. We provided a narrative synthesis of the results and assessed the quantity and quality of evidence for each level of prevention (ie, universal, selective, indicated) and mental health outcome.

findingsWe identified 32 systematic reviews and meta-analyses, which included 354 randomised controlled trials, consisting of over 74 558 children and adolescents. Universal parenting interventions were effective in delaying the initiation of alcohol and cannabis use, but did not have consistent findings in preventing disruptive behaviour and mood disorders. Selective interventions were predominantly beneficial for disruptive behavioural problems across a variety of risk factors. Indicated interventions found substantial and consistent evidence for reducing problems in children with behavioural problems. Caution is warranted when interpreting findings, as the overall confidence rating of most reviews was very low, especially in the reporting of study selection and justifying exclusions in the AMSTAR-2.

conclusionsOur findings highlight the need for robust evidence synthesis. Despite the limitations of the current evidence base, parenting interventions hold promise for preventing mental health disorders.

Indexed as

Mental DisordersParentingAdolescentChildHumansSystematic Reviews as TopicAnxiety disordersChild & adolescent psychiatryDepression & mood disordersImpulse control disorders

Identifiers

PMID40615152
PMCPMC12226942

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.