ArticleGastroenterology2025
Dietary Patterns and Incident Chronic Constipation in Three Prospective Cohorts of Middle- and Older-Aged Adults.
Article in Gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Depressive Symptoms, Dietary Patterns and Other Factors Associated with Constipation in Middle-Aged Adults from Kielce District in Poland: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
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Authors and funding
6 authors.
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Abstract
BACKGROUND &
aimsCurrent literature on diet-constipation associations is limited by small sample sizes and cross-sectional designs. We aimed to comprehensively examine the associations among 5 dietary patterns, their components, and incident constipation.
methodsIn 3 large cohorts, the Nurses' Health Study (NHS), NHSII, and the Health Professional Follow-up Study, we identified chronic constipation based on repeatedly measured self-reported constipation symptoms for ≥12 weeks in the past year. We assessed long-term adherence to 5 dietary patterns (alternate Mediterranean diet [aMED], low-carbohydrate diet, Western diet) and indices (plant-based dietary index [PDI], empirical dietary inflammatory pattern) using validated quadrennial food frequency questionnaires. We used a log-binomial model adjusted for a wide range of confounders, including fiber or ultra-processed food intake, to estimate relative risk (95% confidence interval) for constipation.
resultsIn the pooled cohort of 27,774 (78.4 ± 5.6 years) NHS, 55,906 (60.5 ± 4.6 years) NHSII, and 12,237 (78.6 ± 5.6 years) Health Professional Follow-up Study participants, we documented 7519 incident constipation cases after 2 to 4 years of follow-up. Compared with the lowest quintiles, the top quintiles of aMED and PDI were associated with 16% (9%-22%) and 20% (14%-27%) reduced risk for constipation, whereas the top quintiles of empirical dietary inflammatory pattern, Western diet, and low-carbohydrate diet were associated with 24% (15%-33%), 22% (11%-33%), and 3% (-3% to 11%) increased risk for constipation, respectively. These associations were independent of total fiber or ultra-processed food intake. Vegetable and nut intake, which is enriched in aMED and PDI, was associated with decreased constipation risks.
conclusionOur findings suggest that dietary patterns emphasizing plant-based foods and healthy fats may protect against constipation, informing future dietary interventions and treatments for chronic constipation.
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