Evidence map›Paper›PMID 40614216›Full record

ArticleScience immunology2025

Primate retroelement exonization and sexually dimorphic

Tobias Plowman, Tom Hofland, Callum Hall, Rachael Thompson, Judith Pape, Kevin W Ng, Laura Doglio, George Kassiotis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tobias PlowmanRetroviral Immunology Laboratory, Francis Crick Institute, London, UK.ORCID 0000-0002-0413-0975
Tom HoflandRetroviral Immunology Laboratory, Francis Crick Institute, London, UK.ORCID 0000-0001-8200-7027
Callum HallRetroviral Immunology Laboratory, Francis Crick Institute, London, UK.ORCID 0000-0002-0491-4438
Rachael ThompsonRetroviral Immunology Laboratory, Francis Crick Institute, London, UK.ORCID 0009-0000-7536-523X
Judith PapeRetroviral Immunology Laboratory, Francis Crick Institute, London, UK.ORCID 0000-0002-4225-5568
Kevin W NgRetroviral Immunology Laboratory, Francis Crick Institute, London, UK.
Laura DoglioRetroviral Immunology Laboratory, Francis Crick Institute, London, UK.
George KassiotisRetroviral Immunology Laboratory, Francis Crick Institute, London, UK.ORCID 0000-0002-8457-2633

Funding

Medical Research Council CC2088Wellcome Trust CC2088
6 · The paper itself

Abstract

Type 2 immunity is orchestrated by IL-4 and IL-13 signaling, initiated by binding to receptors that are specific to each cytokine or to the shared heterodimeric receptor comprising the IL-4Rα and IL-13Rα1 subunits. Here, we report that sexually dimorphic

Indexed as

Interleukin-13 Receptor alpha1 SubunitRetroelementsAlternative SplicingAnimalsExonsFemaleHumansInterleukin-13MalePrimatesProtein IsoformsSex CharacteristicsTranscription, GeneticIL13RA1 protein, humanInterleukin-13Interleukin-13 Receptor alpha1 SubunitProtein IsoformsRetroelements

Identifiers

PMID40614216
PMCPMC7617988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.