ArticleScience advances2025
Unleashing the potential of lignin with innovative trifunctional binary deep eutectic solvent strategy: Isolation of uncondensed lignin.
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- An Eco-Efficient and Sustainable Strategy for Fabricating High-Strength Agricultural Fibers.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Conformation-Modulated Lignin for Durable and High-Output Cellulosic Triboelectric Materials Toward Self-Powered Sensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Photoconversion of Xylan to Glyceric Acid Coupled with Hydrogen Evolution Enabled by Coral-Like S-Scheme Heterojunction.Research (Washington, D.C.) · 2026Article
- A lignin-enrichment approach for processing natural wood into highly NIR-selective optical filters.Nature communications · 2025Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Highly efficient conversion of lignin into value-added chemicals and materials is trapped in the inevitable cleavage of β-O-4 linkages and formation of highly condensed structures with deep colors during lignin isolation. Here, we develop a trifunctional choline chloride/glyoxylic acid (ChCl/GA) binary deep eutectic solvent with a π-π conjugate structure and moderate acidity for the fast isolation of light-colored lignin with near proto-structures (exceeding 88% of delignification ratio for 1 hour). The synergetic interaction of GA and ChCl substantially reduced Gibbs free energy of acetal reaction and thoroughly captured reactive intermediates, precisely activating the following key functions: stabilizing β-O-4 linkages, inhibiting condensation reaction, and shielding -OH groups. These enabled efficient isolation of uncondensed, abundant β-O-4 linkage (45.80/100 C9; 79% retention) and light-colored lignin. A near-theoretical yield of aromatic monomers upon depolymerization and high performances as adhesives for lignocellulosic bioplastics were achieved. This work unleashes the valorization potential of lignin by a relatively green and fast strategy for sustainable biorefineries.
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Registered trials
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