Evidence map›Paper›PMID 40614202›Full record

ArticleScience advances2025

Laura Urbach, Lena Wieland, Frederike Penz, Rebecca Diya Samuel, Stefan Küffer, Lukas Klein, Christof Lenz, Ulrich Sax, Michael Ghadimi, Ramona Schulz-Heddergott and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Laura UrbachDepartment of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0002-8034-3120
Lena WielandDepartment of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Göttingen, Germany.
Frederike PenzDepartment of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Göttingen, Germany.
Rebecca Diya SamuelDepartment of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Göttingen, Germany.ORCID 0009-0002-0603-0406
Stefan KüfferInstitute of Pathology, University Medical Center Göttingen, Göttingen, Germany.
Lukas KleinDepartment of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0003-3725-068X
Christof LenzCore Facility Proteomics, University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0002-0946-8166
Ulrich SaxClinical Research Unit 5002 (CRU5002/KFO5002), University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0002-8188-3495
Michael GhadimiClinical Research Unit 5002 (CRU5002/KFO5002), University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0001-8208-1526
Ramona Schulz-HeddergottClinical Research Unit 5002 (CRU5002/KFO5002), University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0002-6483-4392
Elisabeth HessmannDepartment of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Göttingen, Germany.
Volker EllenriederDepartment of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Göttingen, Germany.
Nelson DusettiCentre de Recherche en Cancérologie de Marseille, CRCM, Inserm, CNRS, Institut Paoli-Calmettes, Université Aix-Marseille, Marseille, France.ORCID 0000-0002-6161-8483
Shiv K SinghDepartment of Gastroenterology, Gastrointestinal Oncology and Endocrinology, University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0002-5725-4058

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In ~70% of patients with pancreatic ductal adenocarcinoma, the

Indexed as

Carcinoma, Pancreatic DuctalDrug Resistance, NeoplasmMutation, MissensePancreatic NeoplasmsTranscription, GeneticTumor Suppressor Protein p53AnimalsCell CycleCell Line, TumorGene Expression Regulation, NeoplasticHumansMiceProtein Kinase InhibitorsProtein Kinase InhibitorsTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID40614202
PMCPMC12227071

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.