Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
22 authors.
Gerrit H U LammInstitute of Physical and Theoretical Chemistry, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany.ORCID 0009-0006-6743-2344
Egor MarinGroningen Institute for Biomolecular Sciences and Biotechnology, University of Groningen, 9747AG, Groningen, Netherlands.ORCID 0000-0003-2369-1732
Alexey AlekseevInstitute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075 Göttingen, Germany.ORCID 0000-0001-8990-1662
Anna V SchellbachInstitute of Physical and Theoretical Chemistry, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany.
Artem StetsenkoGroningen Institute for Biomolecular Sciences and Biotechnology, University of Groningen, 9747AG, Groningen, Netherlands.ORCID 0000-0003-3032-3794
Jose Manuel Haro-MorenoEvolutionary Genomics Group, Departamento Producción Vegetal y Microbiología, Universidad Miguel Hernández, Alicante, Spain.ORCID 0000-0002-2113-9269
Samuel L RoseEuropean Synchrotron Radiation Facility, 71 avenue des Martyrs, CS 40220, 38043 Grenoble Cedex 9, France.ORCID 0000-0003-4824-4066
Nicolas CaramelloEuropean Synchrotron Radiation Facility, 71 avenue des Martyrs, CS 40220, 38043 Grenoble Cedex 9, France.ORCID 0000-0003-0025-0213
Antoine RoyantEuropean Synchrotron Radiation Facility, 71 avenue des Martyrs, CS 40220, 38043 Grenoble Cedex 9, France.ORCID 0000-0002-1919-8649
Thomas R SchneiderEuropean Molecular Biology Laboratory, EMBL Hamburg c/o DESY, 22607, Hamburg, Germany.ORCID 0000-0001-6955-7374
Alex BatemanEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, UK.ORCID 0000-0002-6982-4660
Thomas MagerInstitute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075 Göttingen, Germany.ORCID 0000-0002-9571-7033
Tobias MoserInstitute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075 Göttingen, Germany.ORCID 0000-0001-7145-0533
Francisco Rodriguez-ValeraEvolutionary Genomics Group, Departamento Producción Vegetal y Microbiología, Universidad Miguel Hernández, Alicante, Spain.ORCID 0000-0002-9809-2059
Josef WachtveitlInstitute of Physical and Theoretical Chemistry, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany.ORCID 0000-0002-8496-8240
Albert GuskovGroningen Institute for Biomolecular Sciences and Biotechnology, University of Groningen, 9747AG, Groningen, Netherlands.ORCID 0000-0003-2340-2216
Microbial rhodopsins are omnipresent on Earth; however, the vast majority of them remain uncharacterized. Here, we describe a rhodopsin group found in microorganisms from cold environments, such as glaciers, denoted as CryoRhodopsins (CryoRs). A distinguishing feature of the group is the presence of a buried arginine residue close to the cytoplasmic face. Combining single-particle cryo-electron microscopy and x-ray crystallography with rhodopsin activation by light, we demonstrate that the arginine stabilizes an ultraviolet (UV)-absorbing intermediate of an extremely slow CryoRhodopsin photocycle. Together with extensive spectroscopic characterization, our investigations on CryoR1 and CryoR2 proteins reveal mechanisms of photoswitching in the identified group. Our data suggest that CryoRs are sensors for UV irradiation and are also capable of inward proton translocation modulated by UV light.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
CryoRhodopsins: A comprehensive characterization of a group of microbial rhodopsins from cold environments. · full record | OpenQuestion