ArticleMolecular biology and evolution2025
Somatic Evolution of Stem Cell Mutations in Long-Lived Plants.
Article in Molecular biology and evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- A distributive germline restricts the spread of new mutations.bioRxiv : the preprint server for biology · 2026Article
- Transcriptome analysis reveals DNA repair-related clues associated with divergent leaf nuclear DNA diversity inFrontiers in plant science · 2026Article
- Branching architecture limits the number of fixed somatic mutations in trees.G3 (Bethesda, Md.) · 2025Article
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1 author.
Funding
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Abstract
Long-lived perennial plants accumulate numerous somatic mutations with age. Mutations originating in stem cells at the shoot apex often become fixed in large sectors of the plant body due to cell lineage drift during repeated branching. Understanding the somatic evolution of such mutations requires knowledge of the effective stem cell population size, the cellular bottleneck strength during branch initiation, and the mutation rate. Here, we show that these parameters can be estimated directly from cell-layer-enriched DNA sequencing data, thus filling a gap where no other in vivo method exists.
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