ReviewScience China. Life sciences2026
The mechanisms and functions of mitochondria-encapsulating extracellular vesicles.
Review in Science China. Life sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Proteomic comparison of human neural cell-derived extracellular vesicles and parental cells from Alzheimer's disease and cognitively normal individuals.Science China. Life sciences · 2026Article
- M2 microglia-derived migrasome-enriched extracellular vesicles restore mitochondrial homeostasis to orchestrate neurovascular unit recovery after ischemic stroke.Journal of nanobiotechnology · 2026Article
- Mitochondrial homeostasis: the central hub governing the progression of atherosclerosis.Precision clinical medicine · 2026Review
- Mitochondria-Derived Vesicles and Mitochondrial Extracellular Vesicles in Health and Cardiovascular Disease.Circulation research · 2026Review
- Mitochondria transfer: intercellular communication and tumor microenvironment dynamics.Cell communication and signaling : CCS · 2026Review
- Structural and Functional Characterization of EXPO-Derived Extracellular Vesicles in Plants.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Intercellular mitochondrial transfer in melanoma progression and therapeutic resistance: mechanisms and targeting potential.Frontiers in oncology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extracellular vesicles (EVs) are membrane-bound subcellular entities that perform crucial roles in cellular communication and the release of intracellular contents. Traditionally, EVs have been recognized for encapsulating a variety of biomolecules, including DNA, RNA, proteins, and metabolites. However, recent advancements in research have revealed that EVs can also encapsulate organelles, with mitochondria emerging as a significant cargo. This review delves into the burgeoning field of mitochondria-encapsulating EVs, such as mitophers, migrasomes, and exophers, along with other mitochondria-harboring EVs that are less characterized. We explore the discovery, distinctive features, and functional roles of these EVs in regulating mitochondrial quality and quantity, under both physiological and pathological conditions. The mechanisms underlying the generation of these vesicles are also examined. Additionally, we discuss the challenges and future directions in the study of mitochondria-containing EVs. Given their potential to serve as diagnostic biomarkers and therapeutic tools, these mitochondria-embedded vesicles represent a promising frontier in molecular and cell biology, with significant implications for understanding and treating a range of diseases.
Indexed as
Identifiers
40614010What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.