Evidence map›Paper›PMID 40613991›Full record

ArticleRice (New York, N.Y.)2025

RSLpred2: An Integrated Web Server for the Annotation of Rice Proteome Subcellular Localization Using Deep Learning.

Naveen Duhan, Rakesh Kaundal

Abstract read
In one paragraph

Article in Rice (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Naveen DuhanBioinformatics Facility, Center for Integrated BioSystems, Utah State University, Logan, UT, 84322, USA.
Rakesh KaundalBioinformatics Facility, Center for Integrated BioSystems, Utah State University, Logan, UT, 84322, USA. rkaundal@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rice is one of the most important staple crops, providing food for more than one-half of the world's population worldwide. Identifying the localization of encoded proteins is the key to understanding their functional characteristics and facilitating their purification. The prediction of protein localization experimentally is time-consuming due to the need for meticulous experimentation, validation, and data analysis; computational methods provide a quick and accurate alternative. We propose RSLpred-2.0, an extension of our previously developed and widely used RSLpred-1.0 tool for annotating the rice proteome. RSLpred-2.0 is implemented in four levels to accurately predict protein subcellular localization. The first level differentiates between single and dual localization with accuracy (97.66% in 5-fold training/testing, 98.12% on an independent data) and Matthews correlation coefficient (0.88 training, 0.90 independent). Single localized proteins are classified into ten classes at the second level, with accuracy (98.33% in 5-fold training/testing, 98.46% on an independent data) and Matthews correlation coefficient (0.95 training, 0.95 independent). The third level categorizes dual localized proteins into six classes with accuracy (99.20% in 5-fold training/testing, 96.75% on an independent data) and Matthews correlation coefficient (0.98 training, 0.90 independent). The fourth level classifies membrane proteins predicted in level 1 into single-pass and multi-pass membranes with accuracy (99.83% in 5-fold training/testing, 98.81% on an independent data) and Matthews correlation coefficient (0.99 training, 0.97 independent). The RSLpred2 tool will help the researchers understand many organelle-specific functions, cellular processes, and regulatory mechanisms essential for plant growth, development, and response to environmental stimuli. The web server as well as its standalone version of the software developed from this study is available freely at https://kaabil.net/RSLpred2/ .

Identifiers

PMID40613991
PMCPMC12227404

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.