Evidence map›Paper›PMID 40613898›Full record

ArticleSkeletal radiology2025

Costal cartilage mimics urate on DECT.

Anthony J Doyle, Michel K Nieuwoudt, Jason Woon, Hannah M Matthews, Nicola Dalbeth

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Article in Skeletal radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anthony J DoyleAnatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd Grafton, Auckland, 1023, New Zealand. a.doyle@auckland.ac.nz.ORCID http://orcid.org/0000-0003-4561-317X
Michel K NieuwoudtScience Centre, University of Auckland, 302 - Bldg 302, 23 Symonds St, Auckland, 1010, New Zealand.
Jason WoonAnatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd Grafton, Auckland, 1023, New Zealand.
Hannah M MatthewsScience Centre, University of Auckland, 302 - Bldg 302, 23 Symonds St, Auckland, 1010, New Zealand.
Nicola DalbethDepartment of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Room 502-201D, 85 Park Rd Grafton, Auckland, 1023, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo establish whether the material in costal cartilages isoattenuating to urate on dual-energy CT is, in fact, urate. MATERIALS AND

methodsUnder the Human Tissue Act, costal cartilage specimens from 12 donated embalmed cadavers were examined with DECT before and after storage in air, ethanol, and saline. Cadaveric tophi were examined as positive controls. The storage fluid was analyzed for urate. Raman spectroscopy was performed. The results were compared using Student t-tests and ANOVA.

resultsFor cadavers 1-6, initial DECT isoattenuating volumes were 0.3-1.91 cm

conclusionThe isoattenuating material in costal cartilages on DECT is not urate, but other material that simulates the attenuation profile of urate under certain conditions. In clinical practice, isoattenuating material in costal cartilages on DECT can be regarded as artifactual.

Indexed as

Costal CartilageTomography, X-Ray ComputedUric AcidAgedAged, 80 and overCadaverFemaleHumansMaleMiddle AgedSpectrum Analysis, RamanUric AcidArtefactCostal cartilageDual-energy CTGoutMimicUrate

Identifiers

PMID40613898
PMCPMC12552275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.