Evidence map›Paper›PMID 40613837›Full record

ArticlePediatric radiology2025

Utility of cine clips of the spermatic cord in the diagnosis of testicular torsion in the pediatric population.

Cassandra Sams, Eleanor DiBiasio, Rama Ayyala, Grayson Baird, Michael Furman, Alison Hart, Thaddeus Herliczek, David Swenson

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Article in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A Teenager With Testicular Pain.Journal of the American College of Emergency Physicians open · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cassandra SamsBrown University, 125 Metro Center Blvd, Warwick, RI, 02886, USA. cassandra.sams@brownhealth.org.
Eleanor DiBiasioBrown University, 125 Metro Center Blvd, Warwick, RI, 02886, USA.
Rama AyyalaCincinnati Children's Hospital Medical Center, Cincinnati, USA.
Grayson BairdBrown University, 125 Metro Center Blvd, Warwick, RI, 02886, USA.
Michael FurmanBrown University, 125 Metro Center Blvd, Warwick, RI, 02886, USA.
Alison HartMassachusetts General Hospital, Boston, USA.
Thaddeus HerliczekBoston Children's Hospital, Boston, USA.
David SwensonBrown University, 125 Metro Center Blvd, Warwick, RI, 02886, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndirect evidence of testicular torsion, namely lack of blood flow, has been a mainstay in the imaging diagnosis of testicular torsion. Recently, attention has been given to the etiology of testicular torsion, namely the twisted vascular pedicle. However, no study to date has demonstrated the diagnostic yield of inclusion of cine clips of the spermatic cord in identifying this twist.

objectiveThis study seeks to demonstrate whether the inclusion of cine clips of the spermatic cord impacts the diagnostic performance of ultrasound in diagnosing testicular torsion. MATERIALS AND

methodsThis study employed a multi-reader multi-case complete and balanced block cross-over design to assess the diagnostic performance of ultrasound, specifically the impact of cine clips of the spermatic cord. From 1/1/2015 to 12/31/2017, ultrasounds of 156 patients presenting with acute onset of unilateral scrotal pain were reviewed by five pediatric radiologists. Within this data set were 52 cases of surgically confirmed testicular torsion, 52 cases that were abnormal but without testicular torsion, and 52 normal exams. The data set was reviewed twice; initially, static images alone were reviewed. After a period of at least 2 weeks, the data set was again reviewed with the inclusion of cine clips of the spermatic cord. A questionnaire was answered after each review that elicited the radiologist's final diagnosis. Sensitivity and specificity between imaging features were estimated using generalized linear mixed modeling with the GLIMMIX procedure.

resultsWith the inclusion of cine clips of the spermatic cord, the sensitivity in diagnosing testicular torsion increased from 88.8% (95%CI 78.1-94.6%) to 98.5% (95%CI 96.0-99.5%) (P < 0.0001) with no statistically significant change to specificity 98.4% (95%CI 95.9-99.4%) to 97.0% (95%CI 94.9-98.3%) (P = 0.61).

conclusionThis study provides compelling evidence to consider cine clips of the spermatic cord as part of a standard ultrasound approach for the work-up of testicular pain due to the nearly 10% increase in sensitivity in diagnosing testicular torsion with their inclusion.

Indexed as

Spermatic CordSpermatic Cord TorsionAdolescentChildChild, PreschoolCross-Over StudiesHumansInfantMaleSensitivity and SpecificityUltrasonographyCine clipsSpermatic cordTesticular torsion

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.