Evidence map›Paper›PMID 40613751›Full record

ArticleThe oncologist2025

Improving genetics equity: identifying women eligible for genetic care services using mammography clinics in underserved areas as screening hubs.

Darya Kizub, Rachel Bluebond, Sierra Green, Jessica Duckworth, Sreejesh Shanker, Autumn Vara, Banu Arun

Abstract read
In one paragraph

Article in The oncologist, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Darya KizubDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0001-7925-2785
Rachel BluebondDepartment of Clinical Cancer Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sierra GreenDepartment of Clinical Cancer Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jessica DuckworthThe Rose Center for Breast Health Excellence, Houston, TX, USA.
Sreejesh ShankerDepartment of Clinical Cancer Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-7705-8185
Autumn VaraDepartment of Clinical Cancer Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Banu ArunDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-5475-8509

Funding

Susan Komen Foundation CGPR-2019-TX105-THAC46-00012
6 · The paper itself

Abstract

purposeFewer than 20% of underserved individuals undergo guideline-concordant hereditary breast and ovarian cancer (HBOC) genetic testing (GT). Our study aimed to determine the proportion of women eligible for HBOC GT using a cancer genetics risk assessment (CGRA) tool at breast cancer (BC) screening clinics in underserved communities and to describe the program's impact.

methodsParticipants were women who presented for BC screening at The Rose clinics, serving low-income underserved communities in southeast Texas, and completed the CGRA. High-risk individuals received bilingual educational materials and a saliva-based GT kit. Those with a pathogenic variant (PV) or a variant of uncertain significance (VUS) received telegenetic counseling and risk reduction resources.

resultsA total of 501 women completed the CGRA, with 30.1% uninsured. 150 women were identified as eligible for GT, but only 14 (9.9%) completed GT (11 negative, 2 VUS, 1 PV in NF1). GT completion was significantly associated with being White, Native American/Alaskan Native, and Ashkenazi Jewish (P < .05). Hispanic, low-income, and uninsured individuals, or those with fewer relatives with cancer, were as likely to complete GT as others.

conclusionsWe successfully identified underserved women at high risk of HBOC using CGRA, but the GT completion rate was low. However, the completion rate did not differ by Hispanic ethnicity, income, or insurance status, suggesting that financial navigation by our study coordinator, support from Spanish-language staff at The Rose clinics, and the use of Spanish-language educational materials and translation may have helped overcome some barriers.

Indexed as

Breast NeoplasmsEarly Detection of CancerGenetic ServicesGenetic TestingMammographyAdultAgedFemaleHumansMedically Underserved AreaMiddle AgedTexasBRCAbreast cancergenetic counselinggenetic testinghereditary cancermammographyminority populationunderserved

Identifiers

PMID40613751
PMCPMC12231590

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.