Evidence map›Paper›PMID 40613257›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Enhancing early detection of cognitive impairment in primary care with the TabCAT-BHA.

Andrew G Breithaupt, Alissa Bernstein Sideman, Collette Goode, Laura Hill-Sakurai, Mukund Premkumar, Aaron W Scheffler, Anna Chodos, Elena Tsoy, Katherine P Rankin, Joel H Kramer and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. System changes to empower primary care in Alzheimer's disease detection and care.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Enhancing early detection of cognitive impairment in primary care with the TabCAT-BHA.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Andrew G BreithauptMemory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.ORCID 0000-0003-3955-5428
Alissa Bernstein SidemanPhilip R. Lee Institute for Health Policy Studies, University of California, San Francisco, California, USA.
Collette GoodeMemory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.
Laura Hill-SakuraiDepartment of Family and Community Medicine, School of Medicine, University of California, San Francisco, California, USA.
Mukund PremkumarDepartment of Family and Community Medicine, School of Medicine, University of California, San Francisco, California, USA.
Aaron W SchefflerDepartment of Epidemiology & Biostatistics, University of California, San Francisco, California, USA.
Anna ChodosDivision of Geriatrics, University of California, San Francisco, California, USA.
Elena TsoyMemory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.
Katherine P RankinMemory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.
Joel H KramerMemory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.
Nhat BuiMemory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.
Sabrina JarrottMemory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.
Leslie GaynorMemory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.
Odmara L Barreto ChangDepartment of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California, USA.
Christopher ChowMemory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.
James G KahnPhilip R. Lee Institute for Health Policy Studies, University of California, San Francisco, California, USA.
Katherine L PossinMemory and Aging Center, Department of Neurology, University of California, San Francisco, California, USA.

Funding

Building Primary Care Workforce Capacity in the Dementia Diagnostic ProcessR01AG087166 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SIDEMAN, ALISSA BERNSTEIN · 2024 to 2025
$1.6M
Mapping the Dynamics of Caregiver Burden in Alzheimer's DiseaseK01AG059840 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SIDEMAN, ALISSA BERNSTEIN · 2020 to 2024
$652k
NIA NIH HHS K01 AG059840NIA NIH HHS R01 AG087166NINDS NIH HHS UG3/UH3NS105557
6 · The paper itself

Abstract

introductionAs dementia cases increase and new therapies become available, timely diagnosis is critical yet challenging in primary care. We evaluated the TabCAT-Brain Health Assessment (TabCAT-BHA) digital paradigm to assist with early detection and diagnosis.

methodsThis implementation study involved 21 primary care providers (PCPs) serving 2733 eligible patients in a family medicine clinic. PCPs initiated cognitive screening using the TabCAT-BHA, administered by medical assistants, with results integrated into the electronic health record. The study assessed changes in PCP cognitive diagnoses, specialist referrals, and implementation metrics.

resultsTabCAT-BHA was adopted by 95% of PCPs, who were more likely to diagnose cognitive disorders (adjusted odds ratio: 1.72, 95% confidence interval: 1.13-2.62, p = 0.01). Practice-wide diagnosis rates remained elevated after research support ended. PCPs reported increased confidence, reduced stress in diagnosing dementia, and preferred TabCAT-BHA over traditional assessments. DISCUSSION: TabCAT-BHA was well accepted and sustained, offering a scalable solution for cognitive impairment diagnosis in primary care. HIGHLIGHTS: A digital test paradigm increased cognitive impairment diagnoses in primary care. Increased diagnoses across minority groups may mitigate healthcare disparities. Clinicians preferred the digital cognitive assessment over alternative tests. The paradigm decreased clinician stress and increased confidence around diagnosis. Integration with clinic staff workflow yielded high adoption and sustainability.

Indexed as

Cognitive DysfunctionEarly DiagnosisPrimary Health CareAgedDementiaElectronic Health RecordsFemaleHumansMaleMiddle AgedNeuropsychological TestsAlzheimer's diseasedementia managementdiagnosisdigital cognitive assessmentdigital toolsimplementation

Identifiers

PMID40613257
PMCPMC12231204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.