Evidence map›Paper›PMID 40612982›Full record

ArticleSurgical case reports2025

Pulmonary Squamous Cell Carcinoma with Repeated Increases and Decreases in Size.

Yuji Nozaka, Yuji Ohtsuki, Yasushi Horie, Kengo Yasuda, Yuzo Takagi

Abstract readCase Reports
In one paragraph

Article in Surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuji NozakaDepartment of General Thoracic Surgery, Tottori Prefectural Kousei Hospital, Kurayoshi, Tottori, Japan.
Yuji OhtsukiDepartment of Diagnostic Pathology, Tottori Prefectural Kousei Hospital, Kurayoshi, Tottori, Japan.
Yasushi HorieDepartment of Diagnostic Pathology, Tottori Prefectural Kousei Hospital, Kurayoshi, Tottori, Japan.
Kengo YasudaDepartment of Surgery, Division of General Thoracic Surgery, Breast and Endocrine Surgery, Faculty of Medicine, Tottori University, Yonago, Tottori, Japan.
Yuzo TakagiDepartment of General Thoracic Surgery, Tottori Prefectural Kousei Hospital, Kurayoshi, Tottori, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSpontaneous regression of cancer is rare. Although the underlying mechanism is unknown, immunological responses are thought to be involved. CASE PRESENTATION: An 82-year-old Japanese man presented with an incidental bile duct tumor and a dilated common bile duct noted on computed tomography of the abdomen. The scan also showed a 1.1 cm snowball-like shadow in the right lower lobe of the lung. Subsequently, he developed obstructive cholangitis and underwent endoscopic retrograde biliary drainage. Over 4 years of follow-up, the lung nodule repeatedly increased and decreased in size, and new nodules appeared and disappeared. A bronchoscopic biopsy was then performed to evaluate an enlarged nodule, which was consistent with squamous cell carcinoma. He underwent right lower lobectomy with ND1b lymph node dissection. The final diagnosis was pulmonary squamous cell carcinoma (pT1cNXM0).

conclusionsImmune response activation may have caused the observed tumor shrinkage. Careful follow-up is warranted owing to the possibility of regrowth.

Indexed as

cholangitislung cancerspontaneous regressionsquamous cell carcinoma

Identifiers

PMID40612982
PMCPMC12223788

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.