Evidence map›Paper›PMID 40612957›Full record

ArticleFrontiers in immunology2025

Immunomodulatory and anticancer effects of moringa polyherbal infusions: potentials for preventive and therapeutic use.

Wamidh H Talib, Hadeel Shaher Al Junaidi, Heba K Alshaeri, Moudi M Alasmari, Rawan W Hadi, Ahmad Riyad Alsayed, Douglas Law

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. HarnessingInternational journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wamidh H TalibFaculty of Allied Medical Sciences, Applied Science Private University, Amman, Jordan.
Hadeel Shaher Al JunaidiDepartment of Clinical Pharmacy and Therapeutics, School of Pharmacy, Faculty of Pharmacy, Applied Science Private University, Amman, Jordan.
Heba K AlshaeriDepartment of Pharmacology, Faculty of Medicine, King Abdul-Aziz University, Rabigh, Saudi Arabia.
Moudi M AlasmariCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Jeddah, Saudi Arabia.
Rawan W HadiFaculty of Allied Medical Sciences, Applied Science Private University, Amman, Jordan.
Ahmad Riyad AlsayedDepartment of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan.
Douglas LawFaculty of Health and Life Sciences, Inti International University, Nilai, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Plant-based phytochemicals have shown potential as agents against cancer through various biological pathways, including immune system modulation. Combining natural compounds with synergistic interactions enhances the identification of molecular targets in cancer cells, demonstrating anticancer capabilities. The "miracle tree," Aim: This study assesses the anti-tumor and immunomodulatory characteristics of Methods: The MTT assay evaluated the anti-proliferative effectiveness of uncombined Results: The anti-proliferative activity of Moringa-saffron showed the strongest anti-proliferative effect on T47-D and EMT6/P, with IC Conclusion: When combined with saffron or green tea, Moringa can effectively combat cancer and enhance immunomodulatory properties. Further studies are needed to understand the mechanism of action of these herbal infusions.

Indexed as

Antineoplastic Agents, PhytogenicBreast NeoplasmsImmunologic FactorsImmunomodulating AgentsMoringa oleiferaPlant ExtractsAnimalsCell Line, TumorCell ProliferationFemaleHumansMacrophagesMicePhagocytosisAntineoplastic Agents, PhytogenicImmunologic FactorsImmunomodulating AgentsPlant Extractsanticancergreen teaherbal infusionsherbal supplementsimmunomodulatory

Identifiers

PMID40612957
PMCPMC12221896

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.