Evidence map›Paper›PMID 40612948›Full record

ReviewFrontiers in immunology2025

Exosomal proteins: new targets for early diagnosis and treatment of cancer.

Haibin Shen, Meijin Liu, Wentai Yang, Dewang Xiao, Zongbo Peng, Dingyu Rao, Defa Huang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haibin Shen *Laboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Meijin Liu *Laboratory Medicine, People's Hospital of Ganzhou Economic Development Zone, Ganzhou, China.
Wentai Yang *Department of Gastroenterology, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Dewang XiaoThe First School of Clinical Medicine, Gannan Medical University, Ganzhou, China.
Zongbo PengThe First School of Clinical Medicine, Gannan Medical University, Ganzhou, China.
Dingyu RaoDepartment of Cardiothoracic Surgery, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Defa HuangLaboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes are nanoscale, double-membraned vesicles released by a variety of living cells. A wide variety of cargoes, including proteins, DNA and RNA, are transported by exosomes to target cells, thereby transmitting biological signals. In addition to being an essential component of the exosomal cargo, exosomal proteins are a reflection of the physiological state of the originating cell, and play an essential part in intercellular communication in numerous diseases, including cancer. The present review provides a summary of the novel uses of exosomal proteins in cancer diagnosis and prognosis, and highlights the distinct qualities that exosomal proteins possess, when compared with typical serological measurements.

Indexed as

Biomarkers, TumorExosomesNeoplasmsAnimalsEarly Detection of CancerHumansPrognosisBiomarkers, Tumorbiomarkerscancer diagnosisexosomal proteinsexosomestreatment

Identifiers

PMID40612948
PMCPMC12222296

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.