Evidence map›Paper›PMID 40612932›Full record

ArticleOpen forum infectious diseases2025

Retrospective Analysis of the Clinical Significance of Positive Blood Cultures in the Emergency Department: A Single-Center Study.

Farha Ahmed Karlath, Mehboob Ahmed Rehan, Annie Geigor, Michael J Mitchell, Sami Arnaout, Thomas C Greenough, Richard T Ellison

Erratum issuedAbstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Farha Ahmed KarlathDepartment of Medicine, Division of Infectious Diseases & Immunology, UMass Chan Medical School, Worcester, Massachusetts, USA.ORCID https://orcid.org/0000-0002-4245-3919
Mehboob Ahmed RehanDepartment of Medicine, Division of Infectious Diseases & Immunology, United Regional Healthcare System, Wichita Falls, Texas, USA.ORCID https://orcid.org/0000-0002-2535-9998
Annie GeigorUMass Chan Medical School, Worcester, Massachusetts, USA.
Michael J MitchellDepartment of Pathology, UMass Chan Medical School, Worcester, Massachusetts, USA.ORCID https://orcid.org/0009-0002-2299-3341
Sami ArnaoutDepartment of Medicine, Division of Infectious Diseases & Immunology, UMass Chan Medical School, Worcester, Massachusetts, USA.
Thomas C GreenoughDepartment of Medicine, Division of Infectious Diseases & Immunology, UMass Chan Medical School, Worcester, Massachusetts, USA.ORCID https://orcid.org/0000-0002-4132-6977
Richard T EllisonDepartment of Medicine, Division of Infectious Diseases & Immunology, UMass Chan Medical School, Worcester, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There have been major advances in blood culture technology in the last decade, with both faster and more sensitive pathogen detection as well as more precise species identification. We have reassessed the results of positive blood cultures in this new clinical microbiology era with a focus on contaminant identification. Methods: A retrospective study was conducted including all patients with a blood culture collected in 2 UMass Memorial Health emergency departments from September 2019 through April 2020. Contaminants were identified based on standard clinical microbiology laboratory criteria and independent retrospective review by 3 infectious disease (ID) physicians and an ID fellow. Results: Of 5673 blood samples obtained, 5661 were analyzed after 12 were deemed inconclusive by the ID physician review. Blood culture contaminants accounted for 22.5% of the positive blood cultures. Conclusions: The improvements in clinical laboratory technology enable better discrimination of the relative pathogenicity of differing coagulase-negative staphylococci species.

Indexed as

blood cultureCoNScontaminant

Identifiers

PMID40612932
PMCPMC12225663

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.