Evidence map›Paper›PMID 40612855›Full record

ArticleCureus2025

Delayed Diagnosis of Coarctation of the Aorta in a Hypertensive Child: Challenges in Early Detection.

Ryunosuke Hisatomi, Siddharth Mahajan, Ruikang Liu

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ryunosuke HisatomiFamily Medicine, LSU Health Shreveport, Shreveport, USA.
Siddharth MahajanCardiology, LSU Health Shreveport, Shreveport, USA.
Ruikang LiuFamily Medicine, LSU Health Shreveport, Shreveport, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coarctation of the aorta (CoA) remains a frequently underrecognized cause of secondary hypertension in children. We report a case of a preadolescent with persistent, treatment-resistant hypertension initially evaluated with normal echocardiograms and extensive workups, including renal, endocrine, and genetic testing. Importantly, lower extremity blood pressure and femoral pulse assessment were omitted during initial evaluations. After referral to pediatric cardiology, diminished femoral pulses were detected and a third echocardiogram revealed severe CoA, later confirmed by CT angiography. The patient underwent successful stent placement, resulting in blood pressure normalization and discontinuation of all antihypertensive medications. This case highlights the diagnostic pitfalls associated with incomplete physical examination and reliance on a single imaging modality. It reinforces the importance of guideline-based evaluation for pediatric hypertension, including routine assessment of femoral pulses and four-limb blood pressure measurements. In cases of persistent hypertension with high clinical suspicion despite inconclusive initial imaging, repeat echocardiography or advanced imaging should be considered to prevent diagnostic delays and optimize outcomes.

Indexed as

blood pressure measurementcoarctation of the aortact angiographydiagnostic delayechocardiographyfemoral pulsepediatric hypertension

Identifiers

PMID40612855
PMCPMC12225938

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.