Evidence map›Paper›PMID 40612847›Full record

ArticleCureus2025

A Case of Refractory Hidradenitis Suppurativa Successfully Treated With Upadacitinib.

Itsuki Takei, Satoko Shibata-Kikuchi, Ryoma Honda, Takeshi Tokito, Takeshi Nakahara

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Itsuki TakeiDermatology, Kyushu University, Fukuoka, JPN.
Satoko Shibata-KikuchiDermatology, Kyushu Central Hospital, Fukuoka, JPN.
Ryoma HondaDermatology, International University of Health and Welfare Narita Hospital, Chiba, JPN.
Takeshi TokitoOrthopedic Surgery, Kyushu Central Hospital, Fukuoka, JPN.
Takeshi NakaharaDermatology, Kyushu University, Fukuoka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a chronic, disabling inflammatory disease with a high unmet medical need, characterized by persistent, painful skin nodules, abscesses, and draining tunnels. Research on HS is rapidly evolving, with a variety of agents with different mechanisms of action being developed. As several Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathways are involved in the pathogenesis of HS, JAK inhibitors represent a promising therapeutic target. Herein, we present a case of severe hidradenitis suppurativa treated with upadacitinib following the failure of adalimumab and secukinumab.

Indexed as

adalimumabhidradenitis suppurativapsoriasissecukinumabupadacitinib

Identifiers

PMID40612847
PMCPMC12222041

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.