Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) Triggered by Heat Stroke: A Case Report.

Kenko Aoki, Keisuke Suzuki, Takuya Shimada, Rei Ogawa, Kenji Dohi

Abstract readCase Reports

In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kenko AokiDepartment of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, JPN.

Keisuke SuzukiDepartment of Emergency, Critical and Disaster Medicine, Showa University School of Medicine, Tokyo, JPN.

Takuya ShimadaDepartment of Emergency, Critical and Disaster Medicine, Showa University School of Medicine, Tokyo, JPN.

Rei OgawaDepartment of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, JPN.

Kenji DohiDepartment of Emergency, Critical and Disaster Medicine, Showa University School of Medicine, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the first documented case of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) triggered by heat stroke in a man in his mid-50s with no medical history. After experiencing acute symptoms during a heatwave, he was hospitalized. The absence of dehydration and the presence of hyponatremia, along with other laboratory findings, fulfilled the diagnostic criteria for SIADH once other causes were excluded. The linkage between heat stroke and SIADH is thought to involve neuroinflammation and oxidative stress in the hypothalamus, which impacts antidiuretic hormone (ADH) production and secretion. This case highlights critical considerations for emergency and post-acute care in heat-related illnesses, emphasizing the need for vigilant monitoring of SIADH symptoms in patients experiencing heat stroke.

Indexed as

cns complicationsheat strokeoxidative stresssyndrome of inappropriate secretion of antidiuretic hormone (siadh)treatment of hyponatremia

Identifiers

PMID40612844

DOI10.7759/cureus.85304

PMCPMC12226157

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.