Evidence map›Paper›PMID 40612807›Full record

ArticleFrontiers in neurology2025

Altered frontotemporal glucose metabolism following radiotherapy and/or chemotherapy for cervical cancer.

Yao Hu, Yuan Zhong, Yuxiao Hu

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yao HuDepartment of PET/CT Center, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
Yuan ZhongSchool of Psychology, Nanjing Normal University, Nanjing, China.
Yuxiao HuDepartment of PET/CT Center, Jiangsu Cancer Hospital and Jiangsu Institute of Cancer Research and the Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Little is known about the effects of subphrenic radiotherapy on brain glucose metabolism in patients with cervical cancer (CC) after chemotherapy. This study aimed to explore the effects of radiotherapy, chemotherapy, and radiochemotherapy on brain glucose metabolism in patients with CC. Methods: A total of 237 CC patients who underwent Results: Compared to CC patients without treatment, hypometabolism in some frontal and temporal lobes and no hypermetabolic regions were observed in those with radiotherapy ( Conclusion: Radiotherapy might decrease metabolism in the temporal and frontal lobes in CC patients. Furthermore, chemotherapy and radiotherapy might synergistically decrease glucose metabolism in some frontotemporal regions of CC patients, which might indicate potential cognitive impairment and emotional disorders.

Indexed as

brain FDG PETcervical cancerchemotherapyradiochemotherapyradiotherapy

Identifiers

PMID40612807
PMCPMC12222277

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.