ArticlePreventive nutrition and food science2025
Association of Lutein with Cancer: A Systematic Review of the Lutein Effects on Cellular Processes Involved in Cancer Progression.
Article in Preventive nutrition and food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Innovations in the Delivery of Bioactive Compounds for Cancer Prevention and Therapy: Advances, Challenges, and Future Perspectives.Pharmaceuticals (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lutein belongs to the carotenoid family of xanthophylls, which have antioxidant, anti-inflammatory, and anticancer properties. This study aimed to comprehensively review the interactions between lutein and critical cellular processes that influence cancer progression. A search of electronic databases, including PubMed, Science Direct, Cochrane Library, Web of Science, Scopus, Google Scholar, and Google, was conducted for the keywords "cancer or tumor or neoplasm or carcinoma" and "lutein" in the titles or abstracts of published research. A total of 47 studies were reviewed, and it was shown that lutein reduced estrogen receptors (2 out of 4 studies), DNA damage (4 out of 8 studies), cancer cell survival (1 out of 1 studies), growth (7 out of 7 studies), and proliferation (19 out of 19 studies) as well as cancer cell invasion, migration, metastasis, and adhesion (2 out of 2 studies), but induced apoptosis (17 out of 17 studies) and cell differentiation (1 out of 1 studies). According to this review, lutein may be effective in suppressing cellular processes involved in cancer progression through a variety of mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.