Evidence map›Paper›PMID 40612706›Full record

ArticlePediatric diabetes2025

Hypertriglyceridemia in New-Onset Type 1 Pediatric Diabetes.

Colleen A Macke, Iman Al-Gadi, Nidhi Bansal, Sarah K Lyons, Aikaterini A Nella

Abstract readCase Reports
In one paragraph

Article in Pediatric diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Colleen A MackeDivision of Diabetes and Endocrinology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA.ORCID 0009-0007-4321-3742
Iman Al-GadiDivision of Diabetes and Endocrinology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0003-1406-821X
Nidhi BansalDivision of Diabetes and Endocrinology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA.
Sarah K LyonsDivision of Diabetes and Endocrinology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-3686-0112
Aikaterini A NellaDivision of Diabetes and Endocrinology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertriglyceridemia (HTG) in the setting of newly diagnosed diabetes is common in both adult and pediatric populations, as insulin deficiency promotes lipolysis and impairs triglyceride (TG) clearance. Severe HTG (defined as TG levels above 1000 mg/dL) in pediatric patients with new-onset type 1 diabetes mellitus (T1D) is rare; the true incidence and sequela of this phenomenon have not been well characterized. We present a single-center experience on severe HTG in pediatric patients with new-onset T1D between 2013 and 2022 and summarize the cases previously reported in the literature. Our cases display variability in their presentation and in their association with high-risk complications, such as acute pancreatitis. We discuss suggestions of early screening for HTG and pancreatitis in patients with protracted abdominal pain, and close monitoring of those identified to have significant HTG.

Indexed as

Diabetes Mellitus, Type 1HypertriglyceridemiaAdolescentChildChild, PreschoolFemaleHumansMalePancreatitishypertriglyceridemialipidnew-onset diabetespediatrictype 1 diabetes

Identifiers

PMID40612706
PMCPMC12226158

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.