Evidence map›Paper›PMID 40612639›Full record

ArticleRSC advances2025

Insights into anti-tuberculosis drug design on the scaffold of nitroimidazole derivatives using structure-based computer-aided approaches.

Wei Yang, Hui Zhao, Ziting Zhao, Shaojun Pei, Zheng Zhu, Zhen Huang, Yao Zhao, Shuihua Lu, Fangfang Wang, Yanlin Zhao

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wei YangNational Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital Shenzhen 518112 China.ORCID https://orcid.org/0000-0002-9396-329X
Hui ZhaoNational Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital Shenzhen 518112 China.
Ziting ZhaoNational Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital Shenzhen 518112 China.
Shaojun PeiDepartment of Global Health, School of Public Health, Peking University Beijing 100191 China.
Zheng ZhuDepartment of Urology, Xijing Hospital, Air Force Military Medical University Xi'an China.
Zhen HuangNational Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital Shenzhen 518112 China.
Yao ZhaoNational Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital Shenzhen 518112 China.
Shuihua LuNational Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital Shenzhen 518112 China.
Fangfang WangSchool of Life Science, Linyi University Linyi 276000 China.ORCID https://orcid.org/0000-0003-0309-4199
Yanlin ZhaoNational Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital Shenzhen 518112 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deazaflavin-dependent nitroreductase (Ddn) is a crucial enzyme involved in mycolic acid biosynthesis, a vital component of the cell wall in

Identifiers

PMID40612639
PMCPMC12224256

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.