ReviewFrontiers in plant science2025
The biosynthetic pathway of coumarin and its genetic regulation in response to biotic and abiotic stresses.
Review in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Identification and functional annotation of drought-induced molecular pathways in sugarcane using suppression subtractive hybridization.Molecular biology reports · 2026Article
- Bergapten as a Multifunctional Phytochemical in Cancer Therapy: Mechanistic Insights, Pharmacokinetics, and Possible Nanotechnology-Enabled Formulation Strategies.Pharmaceutics · 2026Review
- Metabolic Engineering Strategies for Flavonoid Biosynthesis in Saccharomyces cerevisiae: Current Advances and Future Perspectives.Biotechnology and bioengineering · 2026Review
- Coumarin metabolites in Ocimum: chemical diversity, biosynthetic pathways, and network pharmacology-based prediction of multi-target anticancer potential.Plant molecular biology · 2026Article
- Differences in Chemical Components and Antioxidant Ability Analysis ofInternational journal of molecular sciences · 2026Article
- Imperatorin: A Furanocoumarin with Potential in Combating Cancer Development and Progression-A Comprehensive Review.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Integrated Metabolomic and Transcriptomic Analyses Reveal the Coumarin Biosynthesis Pathway and Key Regulatory Genes in the Pericarp ofPlants (Basel, Switzerland) · 2026Article
- Comparison of the phenolic and antioxidant potential of five European herbal remedies by effect-directed analysis using offline two-dimensional liquid chromatography-high resolution mass spectrometry.Analytical and bioanalytical chemistry · 2026Article
- Effects of laser irradiation on phytochemical composition, histological anatomy, genetic diversity, and food safety of Ocimum basilicum L.BMC plant biology · 2026Article
- Hairy Roots as Producers of Coumarins, Lignans, and Xanthones.Molecules (Basel, Switzerland) · 2025Review
- Analysis and identification of coumarins in different parts ofFrontiers in plant science · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coumarins, a class of metabolites derived from the phenylpropanoid pathway, play critical roles in plant development and interactions with environmental factors. In recent years, numerous studies have revealed that catalytic enzymes, physiological conditions, and environmental stimuli collectively regulate coumarin metabolism in plants. This regulation is not only essential for normal growth and development, but also enhances plant resistance to environmental stresses. In this review, we summarize recent advances in understanding the roles of coumarins in plant development, the key enzymes and genes involved in their biosynthesis, and the genetic regulatory mechanisms that mediate plant responses to both biotic and abiotic stresses, including drought, salinity, UV radiation, and attacks by pathogenic bacteria and insects. The strategic implementation of multi-gene regulatory approaches holds great promise for enhancing plant stress tolerance and has significant potential applications in agriculture.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.