ArticleFrontiers in medicine2025
The hidden impact of myopia severity on interocular suppression in myopia: a cross-sectional study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Objective: This study aimed to investigate the association between spherical equivalent (SE) and interocular suppression in myopic adults, addressing the knowledge gap in functional visual impairments beyond structural changes. Methods: This hospital-based cross-sectional study included 988 myopic patients (aged 18.0-48.7 years, SE ≥ 0.50D). Grating stereopsis (GS), fine stereopsis at 1.5 m (FS1.5), fine stereopsis at 0.8 m (FS0.8), division, fusion, and interocular suppression were examined via computer-based tasks. Multivariate logistic regression analysis and restricted cubic splines (RCSs) were used to analyze the dose-response relationships between SE and the prevalence of suppression disorders (permanent suppression or binocular rivalry suppression). Sensitivity analysis and subgroup analysis were used. Results: The prevalence of suppression disorders was 30.6%. Multivariate logistic regression analysis revealed a dose-response relationship between SE and the prevalence of suppression disorder (odds ratio [OR]: 1.08, 95% CI: 1.00-1.17, Conclusion: Myopia severity independently correlates with suppression disorders, suggesting the need for functional vision screening and personalized myopia correction strategies in high-risk populations.
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