ArticleFrontiers in pediatrics2025
Association between three-timepoint maternal blood pressure trajectories during pregnancy and low birth weight: a longitudinal study based on NHANES 2005-2006.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dynamic changes in maternal blood pressure influence neonatal birth weight however, studies investigating the association between blood pressure trajectories during pregnancy and low birth weight (LBW) remain limited. This study aims to identify maternal blood pressure trajectories based on three time points using group-based trajectory modeling (GBTM) and explore their association with LBW. Methods: This study was based on the NHANES 2005-2006 database and included 330 pregnant women meeting the eligibility criteria (41 cases in the LBW group and 289 in the control group). GBTM was applied to model three blood pressure measurements [systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP)] taken during pregnancy. Multilevel logistic regression was used to assess the relationship between blood pressure trajectories and LBW. Additionally, stratified analyses were conducted to evaluate the modifying effects of age, body mass index (BMI), and education level, and directed acyclic graph (DAG) were employed for covariate selection. Results: Three distinct blood pressure trajectory patterns were identified. Logistic regression revealed that, compared with the low blood pressure trajectory, mothers with a high-medium SBP trajectory had a significantly increased risk of delivering an LBW infant [odds ratio [OR] = 4.479, 95% confidence interval [CI]: 2.541-7.895, Conclusions: Maternal blood pressure trajectories based on three prenatal measurements are closely associated with LBW, particularly among mothers with a high-medium SBP trajectory. This study underscores the importance of monitoring blood pressure fluctuations during pregnancy and suggests that early intervention may help reduce the risk of LBW.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.