Evidence map›Paper›PMID 40612463›Full record

ArticleData in brief2025

Dataset on neuropsychological profile and microbiota composition in cognitively unimpaired elderly and Alzheimer's patients.

Luis Heredia, David Mateo, Nerea Carrión, Margarita Torrente

Abstract read
In one paragraph

Article in Data in brief, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luis HerediaLaboratory of Toxicology and Environmental Health (LSTM), Centre for Environmental, Food and Toxicological Technology (TECNATOX), Universitat Rovira i Virgili, Reus, Spain.
David MateoLaboratory of Toxicology and Environmental Health (LSTM), Centre for Environmental, Food and Toxicological Technology (TECNATOX), Universitat Rovira i Virgili, Reus, Spain.
Nerea CarriónLaboratory of Toxicology and Environmental Health (LSTM), Centre for Environmental, Food and Toxicological Technology (TECNATOX), Universitat Rovira i Virgili, Reus, Spain.
Margarita TorrenteLaboratory of Toxicology and Environmental Health (LSTM), Centre for Environmental, Food and Toxicological Technology (TECNATOX), Universitat Rovira i Virgili, Reus, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article presents data collected from a total of 50 older adults (25 healthy controls and 25 diagnosed with Alzheimer's disease). Among the assessments performed in this sample was a comprehensive neurocognitive screening: including working memory, cognitive flexibility, perception, attention, motor coordination, inhibitory control, verbal fluency and visuo-spatial skills. The data presented also include analysis of the participants' gut microbiota using the shot gun approach in faecal samples. Finally, evaluations of the emotional state, level of functioning and adherence to the Mediterranean lifestyle of all participants are also available. Despite the limited sample size due to challenges in patient recruitment, present data could be useful in the identification of microbial signatures potentially predictive of cognitive decline or AD progression and also for helping to the design of clinical trials targeting the microbiome to assess effects on cognitive function. Furthermore, it is well known that the gut microbiota exhibits significant variability associated with lifestyle habits, diet, and geographic location, underscoring the critical influence of environmental and cultural factors in shaping its composition. These data are of utmost importance when considering regional and lifestyle-related diversity in microbiome research, as they can help researchers explore personalized therapeutic approaches and enhance participant stratification in future clinical trials.

Indexed as

Alzheimer’s diseaseCognitionDementiaGut microbiotaMicrobial diversity

Identifiers

PMID40612463
PMCPMC12221760

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.