ArticleRevista cientifica odontologica (Universidad Cientifica del Sur)
Enamel matrix derivative and root coverage: A literature review.
Article in Revista cientifica odontologica (Universidad Cientifica del Sur). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Application and mechanism study of EMD-Gel composite scaffold in dental pulp tissue repair.Frontiers in bioengineering and biotechnology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: : The use of enamel matrix derivative proteins, also known as Emdogain®, has revolutionized clinical practice in dentistry since the 90s. This biomaterial has demonstrated to promote periodontal tissues regeneration lost due to periodontal disease which persists as a public health problem, emerging as an effective alternative in treatments such as non-surgical periodontal therapy, treatment of furcation lesions, intraosseous defects, and more recently, its use has become especially popular in root coverage surgeries. Objective: : Evaluate studies in reference to the use of enamel-derived matrix proteins in periodontal treatments, to offer a comprehensive and up-to-date vision of its impact and effectiveness. Materials and Methods: : Systematic review was conducted about randomized clinical trials (RCTs) published between 2019 and 2024, using databases PubMed and Scopus, considering Clinical measurements performed in the studies. Results: The analyzed studies compared different surgical techniques for the treatment of gingival recessions, focusing on the percentage of root coverage (RC), clinical attachment gain (CAL), increase in gingival thickness (KTW), long-term stability, and postoperative pain (VAS). Conclusion: EMD significantly contributes to improvement of periodontal regeneration and long-term outcomes of root coverage surgeries, results obtained show a lot of variability. Randomized controlled trials are necessary to evaluate efficacy in different clinical contexts.
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Registered trials
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