Evidence map›Paper›PMID 40612373›Full record

ArticleFrontiers in cardiovascular medicine2025

The relationship between right ventricular functions and early clinical events during hospitalization and after discharge in patients with low ejection fraction heart failure.

Mehdi Onac, Ali Yasar Kılınc, Ahmad Huraibat, Alaa R Al-Ihribar, Umuttan Dogan

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Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Mehdi OnacDepartment of Cardiology, İstanbul Aydın University Medical Faculty Hospital, İstanbul, Türkiye.
Ali Yasar KılıncCardiology Department, Akdeniz University Medical Faculty Hospital, Antalya, Türkiye.
Ahmad HuraibatFaculty of Medicine, İstanbul Aydin University, İstanbul, Türkiye.
Alaa R Al-IhribarCollage of Medicine and Health Sciences, Palestine Polytechnic University, Hebron, Palestine.
Umuttan DoganCardiology Department, Akdeniz University Medical Faculty Hospital, Antalya, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Right ventricular dysfunction is an independent predictor of poor prognosis in the patients with left ventricle failure. In this study, it is aimed to investigate the relationship between RV functions and early clinical events in hospital and after discharge in patients who were followed up for heart failure with a low ejection fraction and were hospitalized with the diagnosis of heart failure. Materials and methods: Seventy patients with a left ventricular ejection fraction below 45% who were hospitalized due to decompensated heart failure were enrolled in this study. They were stabilized after medical treatment and discharged. Thereafter, they were followed up for 6 months in terms of clinical events. Image windows used as standard in the 2D echocardiography technique were recorded while the related technique was being performed. Results: Composite adverse events were observed in 45 patients (64.3%), while composite adverse events were not observed in 25 patients (35.7%). Relation between the independent risk factors and composite adverse events were analyzed with binary logistic regression analysis. Receiver Operating Characteristic (ROC) analysis was performed to determine the distinctive performance of right ventricular (RV) Global Longitudinal Strain (GLS) and RV Free Wall Strain (FWS) parameters in the prediction of mortality in patients. RV Global LS ( Conclusion: We found that RV GLS and RV fwLS are closely related. Moreover, both measurements were correlated not only with parameters reflecting RV systolic function, but also with parameters reflecting LV function.

Indexed as

diastolic dysfunctionleft heart failurelongitudinal 2D strain analysisright ventricle strainspeckle tracking the relationship between right ventricular functions and early clinical events during hospitalization and after discharge in patients with low ejection fraction heart failuretissue Doppler echocardiography

Identifiers

PMID40612373
PMCPMC12224206

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