ReviewFrontiers in oncology2025
Recent advances in biomarker detection of oral squamous cell carcinoma.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- PELP1 expression is associated with disease progression in inflammation-driven oral cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Circulating Tumour Cells as Potential Biomarkers for Oral Squamous Cell Carcinoma.Molecules (Basel, Switzerland) · 2026Review
- Molecular Mechanisms in Oral Squamous Cell Carcinoma: Integrative Roles of Cancer-Associated Fibroblasts, Immune Microenvironment, and Precision Therapeutic Opportunities.International journal of molecular sciences · 2026Review
- Ex vivo HNSCC clinical studies using saliva and antiviral or antibacterial chewing gums reveal reduction in carcinogenic microbes.Scientific reports · 2026Article
- Screening for differentially expressed genes in retinoblastoma gene chips through the GEO database and validation in clinical settings.International journal of ophthalmology · 2026Article
- Deep learning-based artificial intelligence models predict survival in patients with oral cavity squamous cell carcinoma.Scientific reports · 2025Article
- Downregulation of PDIA4 inhibits proliferation and migration in human oral squamous cell carcinoma.Hereditas · 2025Article
- Development and validation of a prediction model for lymph node metastasis in oral squamous cell carcinoma using serum biomarkers.American journal of cancer research · 2025Article
- Evaluation of the role of salivary survivin and caspase-3 in apoptosis regulation in oral submucous fibrosis and oral squamous cell carcinoma among gutka chewers.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral squamous cell carcinoma is among the most prevalent tumours of the oral and maxillofacial region. The initial symptoms are typically minor and may remain misdiagnosed until the disease advances, resulting in a significantly reduced five-year survival rate for patients. Early detection is critical, as it can improve five-year survival rates from below 50% to 70-90%. Due to their reduced sensitivity and intrusive nature, conventional screening methods such as serological testing and histopathological biopsies have limitations in their application. In contrast, emerging technologies including single-cell sequencing, spatial transcriptomics, nanopore sequencing, biosensor technology, and artificial intelligence, among other advanced detection methods, are redefining biomarker discovery. Scalability obstacles still exist, including clinical validation gaps, high implementation costs, and analytical complexity. In order to close the gap between invention and equitable implementation, future efforts should focus on multicenter validation of potential biomarkers and cost-effective integration of these technologies. This will ultimately improve patient prognosis and quality of life. This work aims to comprehensively investigate and evaluate the prospective applications and future developmental potential of these technologies while offering an extensive examination of oral squamous cell cancer biomarker research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.