Evidence map›Paper›PMID 40612344›Full record

ArticleFrontiers in oncology2025

Case Report: Malignant transformation of ganglioneuroma in the rectovaginal septum to malignant peripheral nerve sheath tumor based on neurofibromas.

Xiaoxiao Xi, Hui Cheng, Shanyu Huang, Chen Wang, Mingzhu Ye, Xin Sun

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoxiao XiDepartment of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.
Hui ChengDepartment of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.
Shanyu HuangDepartment of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.
Chen WangDepartment of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.
Mingzhu YeDepartment of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.
Xin SunDepartment of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant peripheral nerve sheath tumor (MPNST) is a type of soft tissue sarcoma that commonly occurs in the trunk, limbs, and head and neck regions, but rarely in the pelvic area. Nearly half of MPNST cases are secondary to neurofibromatosis type 1 (NF1). This case report discusses a 29-year-old woman diagnosed with NF1 and pseudohermaphroditism, who presented with a large mass in the rectovaginal septum. Several years prior, a biopsy had identified the mass as a ganglioneuroma (GN). The mass was surgically removed via a vaginal approach, and postoperative pathology confirmed MPNST arising from NF1. In addition, this report provides a brief review of the relevant literature.

Indexed as

disorder of sex developmentganglioneuromamalignant peripheral nerve sheath tumorneurofibromatosis type 1rectovaginal septumtransvaginal surgery

Identifiers

PMID40612344
PMCPMC12221925

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.