ArticleFrontiers in nutrition2025
Elevated body fat percentage is linked to increased risk of diabetes: a longitudinal retrospective cohort study based on Chinese adults.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Article
- Retrospective cohort study of body fat percentage and incident impaired fasting glucose among Chinese adults.Scientific reports · 2026Article
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4 authors.
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Abstract
Objective: Previous studies have extensively explored the association between body mass index (BMI) and the risk of diabetes. However, evidence regarding the relationship between body fat percentage (BF%) and diabetes risk remained limited. This study aimed to investigate the association between BF% and the risk of diabetes among Chinese adults. Methods: We conducted a retrospective cohort study involving 211,833 Chinese adults who underwent health evaluations from 2010 to 2016. The relationship between baseline BF% and diabetes risk was analyzed using Cox proportional hazards regression models. Additionally, cubic spline functions and smooth curve fitting were used to examine the nonlinear relationship between BF% and diabetes onset. Sensitivity and subgroup analyses were performed to validate the robustness of our findings. Results: After adjusting for the variables, our analysis demonstrated that a 1% increase in BF% is associated with a 1.04-fold higher risk of diabetes (HR: 1.04, 95% CI: 1.04-1.05, Conclusion: This study indicates a positive, nonlinear relationship between BF% and diabetes risk in Chinese adults. Reducing BF% below the identified threshold could significantly lower the risk of developing diabetes.
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