ArticleFrontiers in nutrition2025
Association between dietary multi-metal intake and the risk of diabetic retinopathy: a population-based study.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the association between dietary metals intake and the risk of diabetic retinopathy (DR) in adults with diabetes. Methods: Data from 2,822 U. S. adults with diabetes in National Health and Nutrition Examination Survey (NHANES) 2007-2016 were analyzed. Associations between the intake of six dietary metals and DR risk were assessed using multivariable logistic regression, Weighted Quantile Sum (WQS) regression, and Bayesian Kernel Machine Regression (BKMR). Restricted Cubic Spline (RCS) regression examined the dose-response relationship between intake of dietary metal and DR risk. Mediation analysis explored the underlying mechanisms. Results: Log10-transformed dietary Zinc (Zn) (OR = 0.53, 95% CI 0.35-0.80, Conclusion: In American adults with diabetes, elevated dietary metals intake, especially zinc, may be associated with a lower risk of DR.
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