Evidence map›Paper›PMID 40612305›Full record

ArticleFrontiers in nutrition2025

Association between dietary inflammatory index and periodontitis in American adults: exploring the mediating role of biological aging.

Haoyang Hua, Shencong Xu, Yifan Wang, Yuanna Zheng, Fangyue Xiang

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haoyang Hua *School/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China.
Shencong Xu *School/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China.
Yifan WangUrology & Nephrology Center, Department of Urology, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, China.
Yuanna ZhengSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China.
Fangyue XiangSchool/Hospital of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dietary patterns are associated with inflammatory states. However, there are few reports about its relationship with periodontitis and its mechanism. This study investigated the relationship between dietary inflammatory index (DII) and periodontitis, and the mediating role of biological aging in this relationship. Methods: Data from the National Health and Nutrition Examination Survey from 2009 to 2014 were utilized, including adults aged 20 years and above. The relationship between DII and periodontitis was assessed using multivariate logistic regression analysis, and restricted cubic splines were employed to test for potential non-linear associations. Subgroup analyses were conducted to explore potential influencing factors related to DII and periodontitis. In addition, the mediating role of biological aging in dietary inflammatory indices and periodontitis was further explored. Results: A total of 10,096 participants were included in the study. The results indicated a positive correlation between DII scores and the prevalence of periodontitis. In the fully adjusted model, participants in the highest DII quartile had a 23% higher risk of periodontitis compared to those in the lowest quartile (OR = 1.23, 95% CI: 1.01, 1.48, Conclusion: DII scores were positively associated with the prevalence of periodontitis in U.S. adults, suggesting that dietary patterns may have a significant impact on the prevalence of periodontitis. It also provides further insight into the mechanistic link between biological aging-mediated DII and the development of periodontitis.

Indexed as

dietary inflammatory indexdietary patterninflammationmediating effectperiodontitis

Identifiers

PMID40612305
PMCPMC12222260

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