ArticleMaterials today. Bio2025
Ruthenium-quercetin coordinated nanotherapeutics with macrophage polarization regulation to rapidly promote bacterial-infected wound healing.
Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Enzyme-Flavonoid Synergistic Hydrogel: Enables Glucose-Activated Cascade Acidification and Programmed Drug Release for Diabetic Wound Therapy.Gels (Basel, Switzerland) · 2026Article
- Research progress on self-assembled supramolecular bioactive materials from herbal natural products and their applications in anti-infection field.Materials today. Bio · 2026Review
- Quercetin as a multifaceted neuroprotective agent against cerebral ischaemia-reperfusion injury: mechanisms and therapeutic potential.Frontiers in pharmacology · 2026Review
- Sonodynamic CoMg-Quercetin Nanozyme for Antibacterial Therapy and Multifunctional Bone Regeneration in Infectious Bone Defects.Biomaterials research · 2026Article
- Progress in Research on Macrophage Polarization Mechanisms and Targeted Therapies inInfection and drug resistance · 2025Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hypoxic and inflammatory microenvironment induced by bacterial invasion of wound tissue severely hinders the healing process. In recent years, photothermal therapy (PTT) based on metal-polyphenol coordination networks has garnered considerable attention due to its potent antibacterial effects, biofilm-disrupting capabilities, and intrinsic enzyme-like activities. In this study, a metal-polyphenol coordinated nanotherapeutic system was constructed via synergistic coordination-driven self-assembly between the transition metal ruthenium and quercetin (referred to as QRs). These QRs demonstrated excellent photothermal conversion efficiency and antibacterial performance, while also catalyzing the decomposition of hydrogen peroxide into oxygen under inflammatory conditions. In an
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