Evidence map›Paper›PMID 40612230›Full record

ArticleBiophysics reports2025

Synovial sarcoma extracellular vesicles induce fatty liver.

Tao Ren, Zhiheng Zhou, Huirong Hong, Bohong Cen, Jun Xiao, Guofen Chen, Yang Zhang, Jianlong Li

Abstract read
In one paragraph

Article in Biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tao Ren *Department of Orthopedic, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Zhiheng Zhou *Department of Orthopedic, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Huirong Hong *Department of Orthopedic, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Bohong CenClinical Pharmacy Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Jun XiaoDepartment of Orthopedic, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Guofen ChenDepartment of Orthopedic, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Yang ZhangDepartment of Orthopedic, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Jianlong LiDepartment of Orthopedic, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synovial sarcoma leads to pathological changes in multiple organs. To investigate the mechanism by which synovial sarcoma induces fatty liver through extracellular vesicles (EVs), the synovial sarcoma SW-982 cells were orthotopically implanted, or SW-982 derived EVs were extracted and used to "educate" nude mice. Liver tissues were then subjected to H&E and Oil-Red O (ORO) staining, and qPCR analysis. EVs were characterized using TEM and Nanosight. The bio-distribution of EVs

Indexed as

Extracellular vesicles (EVs)Fatty liverKupffer cells (KCs)Synovial sarcoma

Identifiers

PMID40612230
PMCPMC12213661

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.