ArticleSage open pediatrics
Fever of Unknown Origin in Children: A 14-Year, Single Institution Retrospective Review.
Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Possible Gastroenterological Causes of FUO (Fever of Unknown Origin).Journal of clinical medicine · 2026Review
- Pediatric fever of unknown origin: Diagnostic spectrum revealed by a multidisciplinary retrospective study.European journal of pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: To glean additional knowledge on children with fever of unknown origin (FUO). Methods: Children <18 years old referred to Infectious Disease Service for FUO in a tertiary paediatric hospital were analysed retrospectively from December 2004 to January 2019. Clinical profile, interventions and outcomes were reviewed. Results: There were 272 children evaluated (median age 81.5 months, 56.3% males). Causes identified were infections (54.0%), inflammatory (17.3%), haematology/oncological (6.6%), others/unknown (22.1%). The most common infection was typhoid fever. Kikuchi-Fujimoto Disease was the most common inflammatory cause, while haemophagocytic lymphohistiocytosis was the most common haematology/oncological cause. Children ≥ 5 years were more likely to have an inflammatory cause. Cough was associated with infections; mouth ulcers, joint pain and lymphadenopathy with inflammatory disorders. Hepatomegaly, splenomegaly, anaemia and raised C-reactive protein were associated with haematology/oncological conditions. Conclusions: We provide insights into knowledge of paediatric FUO and identify clinical associations with infection, inflammatory and haematological/oncological conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.