Evidence map›Paper›PMID 40612215›Full record

ArticleSage open pediatrics

The Value of Netrin-1 and Neuron Specific Enolase biomarkers in neonates with Hypoxic İschemic Encephalopathy.

Ahmed Sobhi, Ashraf Hamed Al-Shokary, Moustafa Kotb Elmala, Maha A El Faramawy, Nageh Shehata Ismail, Asmaa Obada Ibrahim, Naglaa M Kamal, Deena Yasir Hussein Omar, Ahmed Elrashed Elshaikh Eltayeb, Abeer Abdel Kader Elsayed Abdel Mageed and 4 more

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Article in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Ahmed SobhiCairo University, Egypt.
Ashraf Hamed Al-ShokaryBenha University, Egypt.
Moustafa Kotb ElmalaNizwa Hospital, Ad Dakhiliyah, Sultanate of Oman.
Maha A El FaramawyBenha University, Egypt.
Nageh Shehata IsmailMinia University, Egypt.
Asmaa Obada IbrahimAin Shams University, Cairo, Egypt.
Naglaa M KamalCairo University, Egypt.ORCID https://orcid.org/0000-0002-8535-3838
Deena Yasir Hussein OmarBurjeel Medical City, Abu Dhabi, United Arab Emirates.
Ahmed Elrashed Elshaikh EltayebDepartment of Health, Abu Dhabi, United Arab Emirates.
Abeer Abdel Kader Elsayed Abdel MageedBurjeel Medical City, Abu Dhabi, United Arab Emirates.
Hatem Hamed ElshorbagyMenoufia University, Shebeen Elkom, Egypt.ORCID https://orcid.org/0000-0002-2219-3179
Ghada Mohamed Abo ElelaBenha University, Egypt.
Omar Ahmed EletrBenha University, Egypt.
Rasha Aguib Hassan AliBenha University, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate netrin-1 (NT-1) and neuron-specific enolase (NSE) in the umbilical cord as biomarkers in HIE stage II/III. Materials and Methods: We included 100 infants with HIE stage II/III and 100 controls. Cord samples were taken to determine the levels of NT-1 and NSE. Results: The HIE group showed significantly higher NT-1 (343.3 ± 100.6 pg/mL) and NSE (55.17 ± 13.4 ng/mL; Conclusion: NT-1 and NSE can be reliable biomarkers for predicting HIE stage II/III.

Indexed as

coolinghypoxic-ischemic encephalopathynetrin-1neuron-specific enolaseperinatal asphyxia

Identifiers

PMID40612215
PMCPMC12220919

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