ReviewSage open pediatrics
The Global Burden of Major Gastrointestinal Anomalies: A Global, Systematic Review of Gastrointestinal Anomaly Birth Prevalence.
Review in Sage open pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Prenatal Diagnosis and Perinatal Management Considerations in Congenital Abdominal Wall Defects: A Case Series and Narrative Review.Journal of personalized medicine · 2026Article
- Congenital Gastrointestinal Malformations in a Romanian Tertiary Centre (2020-2024): A Retrospective Cohort Study of Diagnosis, Distribution, and Outcomes.Diagnostics (Basel, Switzerland) · 2026Article
- Temporal and spatial trends in isolated gastroschisis: a population-based study in a middle-income setting.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
The burden of congenital gastrointestinal (GI) anomalies is poorly understood. The aim of this systematic review to assess the global prevalence of congenital gastrointestinal (GI) anomalies. We conducted a systematic review of global population-level birth prevalence of gastroschisis, omphalocele, intestinal atresia, esophageal atresia, congenital diaphragmatic hernia, Hirschsprung's disease, and anorectal malformation. We identified 103 studies from high and middle-income countries. Gastroschisis was the most reported condition. Studies reported geographic heterogeneity in gastroschisis, omphalocele, esophageal atresia, Hirschsprung's disease, congenital diaphragmatic hernia, and anorectal malformation prevalence. The prevalence of gastroschisis, omphalocele, and Hirschsprung's disease prevalence was reported to have increased over recent decades. Mean prevalence per 10 000 live and total births ranged from 2.1 to 4.4 cases and 1.4 to 3.6 per 10 000 live or total births, respectively. There is limited surveillance for congenital GI anomalies in LICs and potential temporal and geographic trends that need to be further investigated.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.