ArticleJournal of orthopaedics2025
3D-printed titanium vertebra in the treatment of cervical spondylotic myelopathy: A comparative analysis of perioperative, radiographic, and clinical outcomes.
Article in Journal of orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Anterior cervical corpectomy and fusion (ACCF) using a titanium mesh cage (TMC) is associated with a high rate of subsidence. This study aims to evaluate the potential advantages of utilizing 3D-printed titanium vertebrae as an alternative to TMC in ACCF procedures. Methods: A retrospective analysis was conducted on patients who underwent ACCF at our hospital between March 2017 and June 2023. Patient demographics, surgical parameters (operation duration and blood loss), functional assessments (Barthel score, Morse Fall Scale (MFS), anterior cervical corpectomy index (aCCI)), hospitalization duration, costs, postoperative complications, unplanned reoperations, ICU admissions, and patient-reported outcomes (Japanese Orthopedic Association (JOA) score, Visual Analog Scale (VAS) score, Neck Disability Index (NDI) score) were recorded. Radiographic outcomes, including C2-C7 Cobb angles, segmental lordosis, and subsidence, were assessed via lateral cervical spine X-rays. Statistical analysis was performed using the Chi-square test and Mann-Whitney test. Results: A total of 92 patients were included in the study, with 48 patients in the 3D-vertebra group and 44 in the TMC group. Baseline characteristics were comparable between groups. The 3D-vertebra group demonstrated significantly shorter operative time, reduced blood loss, and improved functional scores compared to the TMC group (p < 0.05). Postoperatively, the 3D-vertebra group exhibited lower JOA and VAS scores at both one-week and final follow-up. NDI scores were comparable at one week but were significantly higher in the TMC group at follow-up. While segmental lordosis remained similar between groups, C2-C7 Cobb angles showed significant differences at follow-up. The TMC group experienced an average subsidence of 2.5 mm, whereas the 3D-vertebra group had minimal subsidence. Conclusion: The use of 3D-printed titanium vertebrae in ACCF surgery offers superior perioperative parameters, radiographic outcomes, and clinical scores compared to TMC implants. Further long-term studies are warranted to establish the extended benefits of 3D-printed vertebrae. Limitations should be considered when interpreting the findings, and prospective, randomized controlled studies are warranted to validate our conclusions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.