Evidence map›Paper›PMID 40612090›Full record

ArticleJournal of Brown hospital medicine2025

Warfarin Induced Non-Uremic Calciphylaxis.

Michael Kanan, Farzana Hoque

Abstract readCase Reports
In one paragraph

Article in Journal of Brown hospital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael KananSaint Louis University School of Medicine.
Farzana HoqueDepartment of Internal Medicine Saint Louis University School of Medicine.ORCID https://orcid.org/0000-0002-9281-8138

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calciphylaxis is a rare and life-threatening condition characterized by vascular calcification and thrombosis, typically seen in patients with end-stage renal disease but also associated with long-term warfarin use in non-uremic patients. We present the case of a 78-year-old woman with a mechanical aortic valve on chronic warfarin therapy who developed progressive, painful necrotic skin ulcerations over ten months. Skin biopsy confirmed warfarin-induced non-uremic calciphylaxis. Following shared decision-making, warfarin was discontinued and replaced with low molecular weight heparin, and intravenous sodium thiosulfate was initiated. This case underscores the importance of recognizing non-uremic calciphylaxis in warfarin-treated patients and highlights the need for early diagnosis, multidisciplinary management, and shared decision-making to balance the risks of anticoagulation against serious complications like calciphylaxis.

Indexed as

Calciphylaxisnon-uremic calciphylaxisshared decision makingwarfarinwarfarin induced skin necrosis

Identifiers

PMID40612090
PMCPMC12224331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.