Evidence map›Paper›PMID 40612020›Full record

ReviewLeukemia research reports2025

Diagnostic and taxonomic challenges in chronic myelomonocytic leukemia with lymph node involvement: A case report and mini-review.

Bhaumik Shah, Mitra Abdollahi-Neisani, Pegah Taheri, Asya Varshavsky, Reza Nejati, Nicholas Mackrides

Abstract readReview
In one paragraph

Review in Leukemia research reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bhaumik ShahDepartment of Pathology, Fox Chase Cancer Center, Temple University Health System, Philadelphia, United States.
Mitra Abdollahi-NeisaniDepartment of Pathology, Fox Chase Cancer Center, Temple University Health System, Philadelphia, United States.
Pegah TaheriDepartment of Pathology, Fox Chase Cancer Center, Temple University Health System, Philadelphia, United States.
Asya VarshavskyDepartment of Bone Marrow Transplant and Cellular Therapies, Fox Chase Cancer Center, Temple University Health System, Philadelphia, United States.
Reza NejatiDepartment of Pathology, Fox Chase Cancer Center, Temple University Health System, Philadelphia, United States.
Nicholas MackridesDepartment of Pathology, Fox Chase Cancer Center, Temple University Health System, Philadelphia, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The WHO and ICC classifications lack standardized terminology to define the disease phase of chronic myeloproliferative neoplasms in extramedullary sites, particularly lymph nodes, when infiltrates resemble extramedullary hematopoiesis (EH). We report a lymph node case of extramedullary chronic myelomonocytic leukemia (CMML) in blast phase mimicking EH. Comprehensive genomic profiling, using chromosomal microarray and NGS-based sequencing, identified copy neutral loss of heterozygosity (cn-LOH), previously unreported in extramedullary CMML. We discuss challenges in determining the CMML disease phase in lymph nodes and review the literature to underscore the need for consensus terminology for cases not meeting myeloid sarcoma criteria.

Indexed as

CMLCMMLExtramedullaryLymph node

Identifiers

PMID40612020
PMCPMC12213670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.