Evidence map›Paper›PMID 40612002›Full record

ArticleBiochemistry and biophysics reports2025

AEBP1-GLI1 pathway attenuates the FACT complex dependency of bladder cancer cell survival.

Haruka Kurosu, Norika Yamada, Ritsuko Nakamura, Hideaki Ito, Koji Ohnishi, Akihito Inoko, Miho Riku, Tomoaki Muramatsu, Naoto Sassa, Kenji Kasai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Haruka KurosuDepartment of Urology, Aichi Medical University School of Medicine, Japan.
Norika YamadaDepartment of Pathology, Aichi Medical University School of Medicine, Japan.
Ritsuko NakamuraDepartment of Pathology, Aichi Medical University School of Medicine, Japan.
Hideaki ItoDepartment of Pathology, Aichi Medical University School of Medicine, Japan.
Koji OhnishiDepartment of Pathology, Aichi Medical University School of Medicine, Japan.
Akihito InokoDepartment of Pathology, Aichi Medical University School of Medicine, Japan.
Miho RikuDepartment of Pathology, Aichi Medical University School of Medicine, Japan.
Tomoaki MuramatsuDepartment of Urology, Aichi Medical University School of Medicine, Japan.
Naoto SassaDepartment of Urology, Aichi Medical University School of Medicine, Japan.
Kenji KasaiDepartment of Pathology, Aichi Medical University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The facilitates chromatin transcription (FACT) complex is composed of SSRP1 and SUPT16H subunits and participates in nucleosomal reorganization; hence, FACT inhibitors are considered promising therapeutics for malignant tumors. Here, we show that adipocyte enhancer binding protein 1 (AEBP1) attenuates the dependency of bladder cancer cell survival on the FACT complex

Indexed as

AEBP1ApoptosisBladder cancerDNA damageFACT complexGLI1

Identifiers

PMID40612002
PMCPMC12221834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.