Evidence map›Paper›PMID 40611999›Full record

ArticlemicroPublication biology2025

RIM Mutants Occlude the Effects of Aliphatic Alcohols on

Natalie J Guzikowski, Casey D Gailey, David M Miller Iii, Ege T Kavalali

Abstract read
In one paragraph

Article in microPublication biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Natalie J GuzikowskiPharmacology, Vanderbilt University, Nashville, Tennessee, United States.
Casey D GaileyCell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, United States.
David M Miller IiiCell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, United States.
Ege T KavalaliPharmacology, Vanderbilt University, Nashville, Tennessee, United States.

Funding

Role of SNARE Interactions in Central Synapse FunctionR01NS134128 · NINDS · VANDERBILT UNIVERSITY · PI Ege T Kavalali · 2024 to 2026
$1.3M
NINDS NIH HHS R01 NS134128
6 · The paper itself

Abstract

Biomolecular condensates formed by liquid-liquid phase separation (LLPS) are emerging as a critical organizing principle for synaptic compartmentalization. Aliphatic alcohols are commonly used to disrupt LLPS in biochemical studies and in cells. Here, we tested the impact of aliphatic alcohols at the organismal level in

Identifiers

PMID40611999
PMCPMC12223791

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.