SynthesisFrontiers in microbiology2025
Bibliometric analysis of sepsis and gut microbiota: Trends from 2014 to 2024.
Synthesis in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sepsis is a life-threatening condition characterized by organ dysfunction resulting from a dysregulated host response to infection, with pathological mechanisms closely linked to imbalances in the intestinal flora. While the gut microbiota influences sepsis progression through metabolic and immune regulation, systematic analyses of research trends remain limited. This bibliometric study comprehensively evaluates the sepsis and gut microbiota field from 2014 to 2024. Methods: We analyzed 944 English-language articles from the Web of Science (WOS) Core Collection using CiteSpace, VOSviewer, and other software tools. The bibliometric assessments included analysis of publication trends, collaborative networks, geographic distributions, journal impact, and keyword clustering. Results: A total of 944 publications included contributions from 5,901 authors across 69 countries. These works were published in 405 journals, and cited a total of 45,932 references. The focus of research has transitioned from early topics such as "necrotizing enterocolitis" and "premature infants" to more recent interests on "short-chain fatty acids" (SCFAs) and " Conclusion: The therapeutic potential of the gut microbiota in sepsis is increasingly recognized. Future research should prioritize microbial-targeted therapies, immune-barrier-metabolic network regulation, and integrated traditional Chinese-Western medicine approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.