SynthesisAlzheimer's & dementia : the journal of the Alzheimer's Association2025
The prevalence of apathy in Lewy body dementia: A systematic review and meta-analysis.
Synthesis in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prevalence of apathy in Lewy body dementia: A systematic review and meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Pooled it
- Apathy Assessment in Neurocognitive Disorders: Revisiting a Supportive Clinical Feature for the Early Recognition of Prodromal Dementia With Lewy Bodies.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026Article
- Apathy in dementia with Lewy bodies: Frequency, correlates, and impact on patient and caregiver experiences.Parkinsonism & related disorders · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
introductionApathy is an important syndrome in Lewy body dementia (LBD), although reported prevalences vary. We aimed to estimate the prevalence of apathy in LBD through systematic review and meta-analysis.
methodsFive databases were searched for articles reporting the prevalence of apathy in LBD (dementia with Lewy bodies [DLB] and Parkinson's disease dementia [PDD]) and prodromal/mild cognitive impairment (MCI) LBD. Linear mixed model random effect meta-analysis was performed to determine the prevalence of apathy.
resultsOf 7846 articles identified, 49 met inclusion criteria. The average pooled prevalence of apathy was 57% (95% confidence interval [CI] 52%-63%, I DISCUSSION: Apathy affects more than half of individuals with LBD. The high prevalence in prodromal DLB supports the notion that apathy may assist in more timely and accurate diagnosis of DLB. HIGHLIGHTS: Reported apathy prevalence in Lewy body dementia (LBD) varies widely in the existing literature. The pooled prevalence of apathy was > 50% in LBD and > 40% in prodromal disease stages. Apathy may have utility in earlier, more accurate diagnosis of dementia with Lewy bodies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.