Evidence map›Paper›PMID 40611419›Full record

ReviewProtein and peptide letters2025

The Interaction between miRNAs and 14-3-3ζ Protein in Different Diseases.

Ahmad Fazilat, Alireza Soleimani Mamalo, Salomeh Roshani, Somaieh Razmi, Mohammad Valilo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Protein and peptide letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmad FazilatDepartment of Genetics, Motamed Cancer Institute, Breast Cancer Research Center, ACECR, Tehran, Iran.
Alireza Soleimani MamaloStudent Research Committee, Urmia University of Medical Sciences, Urmia, Iran.
Salomeh RoshaniDepartment of Animal Biology, Faculty of Natural Science, University of Tabriz, Tabriz, Iran.
Somaieh RazmiDepartment of Horticultural Science, Faculty of Agriculture, University of Tabriz, Tabriz, Iran.
Mohammad ValiloStudent Research Committee, Urmia University of Medical Sciences, Urmia, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Members of the 14-3-3 protein family are involved in various cellular processes, including migration, angiogenesis, cell cycle, apoptosis, and signal transduction. Nevertheless, the 14-3-3 family possibly plays a fundamental role in the development of diseases and cancer by regulating various biological pathways. MicroRNAs (miRNAs) are mainly transcribed by RNA polymerase II (pol II), with only a few exceptions involving RNA polymerase III (pol III). They can control cell mechanisms through different pathways. miRNAs inhibit or destroy mRNAs by binding to them. They control intracellular mechanisms by binding to molecules such as the 14-3-3ζ protein. miRNAs play a role in regulating this protein, and by inducing or suppressing it, they contribute to either the development or the prevention of the diseases. Therefore, considering the importance of the 14-3-3ζ protein in different pathways within the body, we decided to investigate the relationship between miRNAs and 14-3-3ζ and clarify their interactions, in this review.

Indexed as

14-3-3 ProteinsMicroRNAsNeoplasmsAnimalsHumansSignal Transduction14-3-3 ProteinsMicroRNAs14-3-3ζ proteinapoptosiscancerintracellular mechanisms.migrationmiRNA

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.